Facebook X-twitter Youtube Linkedin
  • 909-548-4900
Ampac USA logo
  • Home
  • Products
  • Industries
  • Solutions
  • Contact Us
  • Home
  • Products
  • Industries
  • Solutions
  • Contact Us
Home Water Filter

A Novel Method to Characterise Levels of Pharmaceutical Pollution in Large-Scale Aquatic Monitoring Campaigns

Sammy Farag by Sammy Farag
August 1, 2019
Share on FacebookShare on Twitter

By:Wilkinson, JL (Wilkinson, John L.)[ 1 ] ; Boxall, ABA (Boxall, Alistair B. A.)[ 1 ] ; Kolpin, DW (Kolpin, Dana W.)[ 2 ]

View ResearcherID and ORCID

APPLIED SCIENCES-BASEL

Volume: 9

Issue: 7

Article Number: 1368

DOI: 10.3390/app9071368

Published: APR 1 2019

Document Type:Article

Abstract

Much of the current understanding of pharmaceutical pollution in the aquatic environment is based on research conducted in Europe, North America and other select high-income nations. One reason for this geographic disparity of data globally is the high cost and analytical intensity of the research, limiting accessibility to necessary equipment. To reduce the impact of such disparities, we present a novel method to support large-scale monitoring campaigns of pharmaceuticals at different geographical scales. The approach employs the use of a miniaturised sampling and shipping approach with a high throughput and fully validated direct-injection High-Performance Liquid Chromatography-Tandem Mass Spectrometry method for the quantification of 61 active pharmaceutical ingredients (APIs) and their metabolites in tap, surface, wastewater treatment plant (WWTP) influent and WWTP effluent water collected globally. A 7-day simulated shipping and sample stability assessment was undertaken demonstrating no significant degradation over the 1-3 days which is typical for global express shipping. Linearity (r(2)) was consistently 0.93 (median = 0.99 +/- 0.02), relative standard deviation of intra- and inter-day repeatability and precision was <20% for 75% and 68% of the determinations made at three concentrations, respectively, and recovery from Liquid Chromatography Mass Spectrometry grade water, tap water, surface water and WWTP effluent were within an acceptable range of 60-130% for 87%, 76%, 77% and 63% of determination made at three concentrations respectively. Limits of detection and quantification were determined in all validated matrices and were consistently in the ng/L level needed for environmentally relevant API research. Independent validation of method results was obtained via an interlaboratory comparison of three surface-water samples and one WWTP effluent sample collected in North Liberty, Iowa (USA). Samples used for the interlaboratory validation were analysed at the University of York Centre of Excellence in Mass Spectrometry (York, UK) and the U.S. Geological Survey National Water Quality Laboratory in Denver (Colorado, USA). These results document the robustness of using this method on a global scale. Such application of this method would essentially eliminate the interlaboratory analytical variability typical of such large-scale datasets where multiple methods were used.

http://cel.webofknowledge.com/InboundService.do?customersID=Alerting&smartRedirect=yes&mode=FullRecord&IsProductCode=Yes&product=CEL&Init=Yes&Func=Frame&action=retrieve&SrcApp=Alerting&SrcAuth=Alerting&SID=8AdTUBTY5XPVTD5B2R7&UT=WOS%3A000466547500103

 

The post A Novel Method to Characterise Levels of Pharmaceutical Pollution in Large-Scale Aquatic Monitoring Campaigns appeared first on Facts About Water.

Source: Water Feed

Tags: RO
Sammy Farag

Sammy Farag

Next Post

Prenatal exposure to PFOS and PFOA in a pregnant women cohort of Catalonia, Spain

Comments 2

  1. Открыть счет в binance says:
    2 weeks ago

    I don’t think the title of your enticle matches the content lol. Just kidding, mainly because I had some doubts after reading the enticle. https://www.binance.info/en-NG/register?ref=JHQQKNKN

    Reply
  2. binance signup says:
    10 hours ago

    Thanks for sharing. I read many of your blog posts, cool, your blog is very good.

    Reply

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Recommended.

RO Remineralization Filter

How Important Is the RO Remineralization Filter?

October 9, 2017
How Hard Water Is Harming Your Skin And How To Protect It?

How Hard Water Is Harming Your Skin And How To Protect It?

June 21, 2022

Subscribe.

Trending.

Which US States Have the Best Water Quality? Get the Answer Here

Which US States Have the Best Water Quality? Get the Answer Here

August 25, 2021
Reverse Osmosis Pool cleaners as a substitute for chlorine

Reverse Osmosis Pool cleaners as a substitute for chlorine

September 19, 2017
Reverse Osmosis system Troubleshooting: Fix 7 Common Problems

Reverse Osmosis system Troubleshooting: Fix 7 Common Problems

December 30, 2024
Water filter guide in USA

Water filter guide in USA

August 5, 2025
Deionized Water Vs. Distilled Water- Everything You Need to Know

Deionized Water Vs. Distilled Water- Everything You Need to Know

January 23, 2023

AMPAC USA 2262 S 1200 W Suite #103 Woods Cross, UT 84087

US Phone: (909) 548-4900

ABOUT US

Welcome to Ampac USA’s sophisticated water purification systems, which are designed to tackle the most challenging water purification, water supply, wastewater treatment, and seawater desalination challenges in the world’s harshest settings.

KNOW MORE ABOUT

  • Home
  • Products
  • Industries
  • Solutions
  • Contact Us
  • Home
  • Products
  • Industries
  • Solutions
  • Contact Us

INFORMATION LINKS

  • About Us
  • Privacy Policy
  • Disclaimer Policy
  • Terms & Conditions
  • Delivery Information
  • Sitemap
  • About Us
  • Privacy Policy
  • Disclaimer Policy
  • Terms & Conditions
  • Delivery Information
  • Sitemap

CUSTOMER SUPPORT

Get updates on special events and receive your first drink on us!

Facebook X-twitter Youtube Linkedin
No Result
View All Result
  • Home
  • Review
  • Apple
  • Applications
  • Computers
  • Gaming
  • Gear
    • Audio
    • Camera
    • Smartphone
  • Microsoft
  • Photography
  • Security

© 2025 JNews - Premium WordPress news & magazine theme by Jegtheme.