{"id":420,"date":"2017-07-26T15:47:51","date_gmt":"2017-07-26T15:47:51","guid":{"rendered":"https:\/\/www.ampac1.com\/blog\/effect-of-increased-water-intake-on-plasma-copeptin-in-healthy-adults\/"},"modified":"2026-05-03T20:22:10","modified_gmt":"2026-05-04T03:22:10","slug":"effect-of-increased-water-intake-on-plasma-copeptin-in-healthy-adults","status":"publish","type":"post","link":"https:\/\/www.ampac1.com\/blog\/effect-of-increased-water-intake-on-plasma-copeptin-in-healthy-adults\/","title":{"rendered":"Effect of increased water intake on plasma copeptin in healthy adults"},"content":{"rendered":"

Quick Answer:<\/strong> Copeptin is a stable peptide. It’s released with vasopressin, an antidiuretic hormone, when your body is stressed by osmosis or dehydration<\/a>. Studies show that if you’re a healthy adult who’s a little dehydrated, drinking more water<\/a>-from-sugar-sweetened-beverages-with-water-intake-among-us-children-and-young-adults-in-the-2011-2016-national-health-and-nutrition-examination-survey\/”>water<\/a> each day significantly lowers your plasma copeptin levels. These levels are a good marker for how well hydrated you are. Advanced water treatment, like reverse osmosis, offers great ways to tackle water quality issues in this area. Here at AMPAC USA, we build our commercial and industrial systems to handle these specific water treatment needs, and they come with certified, documented performance.<\/p>\n

\\\\nPublished online: June 3 2017 European Journal of Nutrition (IF 3.239). Guillaume Lemetais \u00b7 Olle Melander \u00b7 Mariacristina Vecchio \u00b7 Jeanne H. Bottin \u00b7\\\\nSofa Enh\u00f6rning \u00b7 Erica T. Perrier\\\\n<\/p>\n

\\\\n<\/p>\n

Abstract<\/h3>\n

\\\\n<\/p>\n

\\\\n<\/p>\n

PURPOSE:<\/h4>\n

\\\\nDifferences in plasma copeptin levels between individuals are linked to things like developing type 2 diabetes, worsening kidney disease, and cardiovascular problems. We wanted to see if 24-hour urine osmolality connected with plasma copeptin. Also, could drinking more water daily actually change circulating plasma copeptin levels?\\\\n<\/p>\n

METHODS:<\/h4>\n

\\\\nThis was a forward-looking study, all done at one research center. We included 82 healthy adults, averaging 23.6 years old, with an average BMI of 22.2 kg\/m2<\/sup>, and half were women. We split them into groups based on how much fluid they usually drank daily: arm A (50-80% of EFSA recommendations), arm B (81-120%), and arm C (121-200%). After an initial visit, people in arms A and B started drinking more water to match arm C for six weeks straight.\\\\n<\/p>\n

RESULTS:<\/h4>\n

\\\\nAt the start, plasma copeptin showed a strong, positive link with 24-hour urine osmolality (p = 0.002) and 24-hour urine specific gravity (p = 0.003). It didn’t connect with plasma osmolality (p = 0.18), 24-hour urine creatinine (p = 0.09), or total fluid intake (p = 0.52). Over the six weeks, copeptin significantly dropped from 5.18 (3.3;7.4) to 3.90 (2.7;5.7) pmol\/L (p = 0.012). During that time, urine osmolality and urine specific gravity also went down, from 591 \u00b1 206 to 364 \u00b1 117 mOsm\/kg (p < 0.001) and from 1.016 \u00b1 0.005 to 1.010 \u00b1 0.004 (p < 0.001) respectively.\\\\n\n\n

CONCLUSIONS:<\/h4>\n

\\\\nAt the study’s start, copeptin levels in the bloodstream were positively linked to how concentrated the urine was over 24 hours in young, healthy people who drank different amounts of fluid. Plus, this study is the first to show that drinking more water for six weeks actually lowers circulating copeptin.\\\\n<\/p>\n

CLINICAL TRIAL REGISTRATION NUMBER:<\/h4>\n

\\\\nNCT02044679.\\\\n\\\\n<\/p><\/div>\n

\\\\n<\/p><\/div>\n

\\\\n<\/p>\n

\\\\n<\/p>\n

KEYWORDS:<\/h4>\n

\\\\nCopeptin; Fluid intake; Hydration; Urine osmolality; Water intake\\\\n\\\\n<\/p><\/div>\n

\\\\nEffect of increased water intake on plasma copeptin in healthy adults\\\\n\\\\n \\\\n\\\\nThe post Effect of increased water intake on plasma copeptin in healthy adults appeared first on Facts About Water.\\\\n\\\\nSource: Water Feed<\/p>\n","protected":false},"excerpt":{"rendered":"

Inter-individual variation in median plasma copeptin is associated with incident type 2 diabetes mellitus, progression of chronic kidney disease, and cardiovascular events<\/p>\n","protected":false},"author":1,"featured_media":88012,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[24,29],"tags":[22],"class_list":["post-420","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-water-filter","category-water-treatment","tag-ro"],"_links":{"self":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts\/420","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/comments?post=420"}],"version-history":[{"count":5,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts\/420\/revisions"}],"predecessor-version":[{"id":88088,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts\/420\/revisions\/88088"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/media\/88012"}],"wp:attachment":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/media?parent=420"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/categories?post=420"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/tags?post=420"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}