{"id":1445,"date":"2020-12-14T01:31:52","date_gmt":"2020-12-14T01:31:52","guid":{"rendered":"https:\/\/www.ampac1.com\/blog\/drinking-water-nitrate-and-cancer-risk-a-systematic-review-and-meta-analysis\/"},"modified":"2026-04-13T16:13:14","modified_gmt":"2026-04-13T16:13:14","slug":"drinking-water-nitrate-and-cancer-risk-a-systematic-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/www.ampac1.com\/blog\/drinking-water-nitrate-and-cancer-risk-a-systematic-review-and-meta-analysis\/","title":{"rendered":"Drinking-water nitrate and cancer risk: A systematic review and meta-analysis"},"content":{"rendered":"

By:\u00a0<\/span><\/b>Essien, Eno E.<\/span><\/a><\/b>;\u00a0<\/span><\/b>Said Abasse, Kassim<\/span><\/a><\/b>;\u00a0<\/span><\/b>Cote, Andre<\/span><\/a><\/b>; et al.<\/span><\/b><\/p>\n

ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH\u00a0<\/span><\/a><\/b>\u00a0\u00a0\u00a0\u00a0<\/span><\/b><\/p>\n

Early Access: NOV 2020<\/span><\/b><\/p>\n

Background<\/a><\/span><\/p>\n

Nitrate is an inorganic compound that occurs naturally in all surface and groundwater, although higher concentrations tend to occur only where fertilizers are used on the land. The regulatory limit for nitrate in public drinking water supplies was set to protect against infant methemoglobinemia, but other health effects were not considered. Risk of specific cancers and congenital disabilities may be increased when the nitrate is ingested, and nitrate is reduced to nitrite, which can react with amines and amides by nitrosation to form N-nitroso compounds which are known animal carcinogens. This study aims to evaluate the association between nitrate ingested through drinking water and the risk of developing cancers in humans.<\/a><\/span><\/p>\n

Methods<\/a><\/span><\/p>\n

We performed a systematic review following PRISMA and MOOSE guidelines. A literature search was performed using PubMed, EMBASE, the Cochrane Library databases, Web of Science and Google Scholars in the time-frame from their inception to January 2020, for potentially eligible publications. STATA version 12.0 was used to conduct meta-regression and a two-stage meta-analysis.<\/a><\/span><\/p>\n

Results<\/a><\/span><\/p>\n

A total of 48 articles with 13 different cancer sites were used for analysis. The meta-regression analysis showed stomach cancer had an association with the median dosage of nitrate from drinking water (t = 3.98, p = 0.0001, and adjusted R-squared = 50.61%), other types of cancers didn\u2019t show any association. The first stage of meta-analysis showed there was an association only between the risk of brain cancer & glioma (OR = 1.15, 95% CI: 1.06, 1.24) and colon cancer (OR = 1.11, 95% CI: 1.04, 1.17) and nitrate consumption in the analysis comparing the highest ORs versus the lowest. The 2(nd) stage showed there was an association only between the risk colon cancer (OR = 1.14, 95% CI: 1.04, 1.23) and nitrate consumption in the analysis comparing all combined higher ORs versus the lowest.<\/a><\/span><\/p>\n

Conclusion<\/a><\/span><\/p>\n

This study showed that there is an association between the intake of nitrate from drinking water and a type of cancer in humans. The effective way of controlling nitrate concentrations in drinking water is the prevention of contamination (water pollution). Further research work on this topic is needed.<\/a><\/span><\/p>\n

https:\/\/apps.webofknowledge.com\/full_record.do?product=WOS&search_mode=AlertSummary&qid=4&SID=C29NbIxAZf9vqUvePQt&page=1&doc=8<\/a><\/p>\n

https:\/\/pubmed.ncbi.nlm.nih.gov\/33138742\/<\/a><\/p>\n

The post Drinking-water nitrate and cancer risk: A systematic review and meta-analysis<\/a> appeared first on Facts About Water<\/a>.<\/p>\n

Source: Water Feed<\/p>\n

<\/p>\n

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Frequently Asked Questions<\/h2>\n
\n

How quickly can an emergency water purification unit be deployed?<\/h3>\n
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AMPAC USA's EPRO and mobile RO units can be operational within 30\u201360 minutes of arrival on-site. Trailer-mounted and skid-mounted systems are pre-plumbed and pre-wired, requiring only connection to a power source and water source. Units treat river water, lake water, or brackish groundwater.<\/p>\n<\/div>\n<\/div>\n

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What flow rates are available for emergency water treatment?<\/h3>\n
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AMPAC USA's emergency systems range from 1,500 GPD portable units to 50,000+ GPD trailer-mounted systems. Military-specification units are available for forward operating base deployment, producing potable water meeting EPA and WHO drinking water standards from virtually any source.<\/p>\n<\/div>\n<\/div>\n

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Are emergency RO systems suitable for disaster relief operations?<\/h3>\n
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Yes. AMPAC USA's emergency systems are used by FEMA, the U.S. military, and international NGOs for disaster relief. They treat flood water, contaminated groundwater, and brackish sources, removing bacteria, viruses, and chemical contaminants to produce safe drinking water on-site.<\/p>\n<\/div>\n<\/div>\n

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What power sources can emergency water purification systems use?<\/h3>\n
\n

AMPAC USA's emergency systems can run on generator power (120\/240V or 480V 3-phase), solar panels with battery backup, or vehicle power take-off (PTO). Low-power models consume as little as 0.5 kW, making them viable for off-grid deployment.<\/p>\n<\/div>\n<\/div>\n

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How durable are military-grade water purification systems?<\/h3>\n
\n

AMPAC USA's military systems are built to MIL-SPEC standards with stainless steel frames, powder-coated components, and UV-resistant materials. They are designed to operate in temperatures from -20\u00b0F to 120\u00b0F and are vibration-tested for transport in military vehicles.<\/p>\n<\/div>\n<\/div>\n<\/div>\n

<\/p>\n

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Conclusion<\/h2>\n

This post highlighted how emergency and military-grade water purification systems provide safe drinking water rapidly in the most challenging field conditions. For organizations requiring deployable water treatment capability, AMPAC USA engineers portable and trailer-mounted systems built to perform wherever they are needed. Contact our team at info@ampac1.com or (909) 548-4900 to discuss your emergency water treatment requirements.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Nitrate is an inorganic compound that occurs naturally in all surface and groundwater, although higher concentrations tend to occur<\/p>\n","protected":false},"author":1,"featured_media":87927,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":[],"rop_publish_now_history":[],"rop_publish_now_status":"pending","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[24],"tags":[22],"class_list":["post-1445","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-water-filter","tag-ro"],"_links":{"self":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts\/1445","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/comments?post=1445"}],"version-history":[{"count":2,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts\/1445\/revisions"}],"predecessor-version":[{"id":88322,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts\/1445\/revisions\/88322"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/media\/87927"}],"wp:attachment":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/media?parent=1445"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/categories?post=1445"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/tags?post=1445"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}