{"id":1201,"date":"2019-08-01T01:58:09","date_gmt":"2019-08-01T01:58:09","guid":{"rendered":"https:\/\/www.ampac1.com\/blog\/a-novel-method-to-characterise-levels-of-pharmaceutical-pollution-in-large-scale-aquatic-monitoring-campaigns\/"},"modified":"2026-06-30T03:59:57","modified_gmt":"2026-06-30T03:59:57","slug":"a-novel-method-to-characterise-levels-of-pharmaceutical-pollution-in-large-scale-aquatic-monitoring-campaigns","status":"publish","type":"post","link":"https:\/\/www.ampac1.com\/blog\/a-novel-method-to-characterise-levels-of-pharmaceutical-pollution-in-large-scale-aquatic-monitoring-campaigns\/","title":{"rendered":"A Novel Method to Characterise Levels of Pharmaceutical Pollution in Large-Scale Aquatic Monitoring Campaigns"},"content":{"rendered":"<div class=\"block-record-info\">\n<p class=\"FR_field\"><span class=\"FR_labelBy:<\/span>Wilkinson, JL (Wilkinson, John L.)<sup><b>[ <1 ] <\/b><\/sup>; Boxall, ABA (Boxall, Alistair B. A.)<sup><b>[ <1 ] <\/b><\/sup>; Kolpin, DW (Kolpin, Dana W.)<sup><b>[ <2 ]<\/b><\/sup><\/p>\n<p><span id=\"show_resc_blurb_link\" class=\"FR_label\"><a class=\"snowplow-view-ResearcherID-and-ORCID\" title=\"View author identifiers such as ResearcherID or ORCID.View ResearcherID and ORCID<\/a><\/span><\/p>\n<\/div>\n<div class=\"block-record-info block-record-info-source\">\n<p class=\"sourceTitleAPPLIED SCIENCES-BASEL<\/p>\n<div class=\"block-record-info-source-values\">\n<p class=\"FR_field\"><span class=\"FR_labelVolume:<\/span> 9<\/p>\n<p class=\"FR_field\"><span class=\"FR_labelIssue:<\/span> 7<\/p>\n<\/div>\n<p class=\"FR_field\"><span class=\"FR_labelArticle Number:<\/span> 1368<\/p>\n<p class=\"FR_field\"><span class=\"FR_labelDOI:<\/span> 10.3390\/app9071368<\/p>\n<p class=\"FR_field\"><span class=\"FR_labelPublished:<\/span> APR 1 2019<\/p>\n<p class=\"FR_field\"><span class=\"FR_labelDocument Type:<\/span>Article<\/p>\n<\/div>\n<div class=\"block-record-info\">\n<div class=\"Abstract<\/div>\n<p class=\"FR_fieldWe know a lot about pharmaceutical pollution in aquatic environments, but most of that research comes from Europe, North America, and other wealthy nations. Why the gap? Well, this kind of research is expensive and needs specialized equipment, making it tough for many places to access. We're changing that. We've come up with a smart new way to monitor pharmaceuticals on a <a href=\"https:\/\/www.ampac1.com\/blog\/why-is-large-scale-seawater-treatment-still-unconventional\/\">large<\/a> scale, no matter where you are.<\/p>\n<p class=\"FR_fieldOur method uses tiny samples you can easily ship. Then, we use a super-efficient, fully tested direct-injection High-Performance Liquid Chromatography-Tandem Mass Spectrometry process. This lets us measure 61 active pharmaceutical ingredients (APIs) and their breakdown products in tap water, surface water, and water from wastewater treatment plants - both before and after treatment - collected from anywhere in the world. We even ran a 7-day test to see if samples degraded during shipping. Good news: they didn't significantly degrade over the 1-3 days it typically takes for global express shipping.<\/p>\n<p class=\"FR_fieldThe numbers look great too. Our linearity (r(2)) was consistently 0.93 (with a median of 0.99 +\/- 0.02). For 75% of our tests at three different concentrations, the relative standard deviation for repeatability and precision was under 20%. Plus, we recovered 60-130% of the APIs from various water types - 87% from LC-MS grade water, 76% from tap water, 77% from surface water, and 63% from WWTP effluent - all within an acceptable range. We also figured out the detection and quantification limits for all tested water types. They were consistently at the nanogram-per-liter level, which is exactly what we need for environmental API research.<\/p>\n<p class=\"FR_fieldTo make sure our method was solid, we had an independent check. We sent three surface water samples and one WWTP effluent sample from North Liberty, Iowa (USA) to two different labs: the University of York Centre of Excellence in Mass Spectrometry (York, UK) and the U.S. Geological Survey National Water Quality Laboratory in Denver (Colorado, USA). Both labs got consistent results, proving our method works globally. This approach means we can finally get rid of the inconsistent analytical results that often pop up when large-scale studies use many different methods. Isn't that a relief?<\/p>\n<p><a href=\"http:\/\/cel.webofknowledge.com\/InboundService.do?customersID=Alerting&amp;smartRedirect=yes&amp;mode=FullRecord&amp;IsProductCode=Yes&amp;product=CEL&amp;Init=Yes&amp;Func=Frame&amp;action=retrieve&amp;SrcApp=Alerting&amp;SrcAuth=Alerting&amp;SID=8AdTUBTY5XPVTD5B2R7&amp;UT=WOS%3A000466547500103\" target=\"_blank\" &quot;noopener \/a rel=\"nofollow noopener\"><\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<p>The post <a href=\"http:\/\/cel.webofknowledge.com\/InboundService.do?customersID=Alerting&amp;smartRedirect=yes&amp;mode=FullRecord&amp;IsProductCode=Yes&amp;product=CEL&amp;Init=Yes&amp;Func=Frame&amp;action=retrieve&amp;SrcApp=Alerting&amp;SrcAuth=Alerting&amp;SID=8AdTUBTY5XPVTD5B2R7&amp;UT=WOS%3A000466547500103#new_tab\" &quot;A Novel Method to Characterise Levels of Pharmaceutical Pollution in Large-Scale Aquatic Monitoring \/a rel=\"nofollow noopener\" target=\"_blank\"> appeared first on <a href=\"https:\/\/thefactsaboutwater.org\" &quot;Facts About \/a rel=\"nofollow noopener\" target=\"_blank\">.<\/p>\n<p>Source: Water Feed<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Much of the current understanding of pharmaceutical pollution in the aquatic environment is based on research conducted in Europe<\/p>\n","protected":false},"author":1,"featured_media":87978,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[24,29],"tags":[22],"class_list":["post-1201","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-water-filter","category-water-treatment","tag-ro"],"_links":{"self":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts\/1201","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/comments?post=1201"}],"version-history":[{"count":3,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts\/1201\/revisions"}],"predecessor-version":[{"id":89491,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/posts\/1201\/revisions\/89491"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/media\/87978"}],"wp:attachment":[{"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/media?parent=1201"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/categories?post=1201"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ampac1.com\/blog\/wp-json\/wp\/v2\/tags?post=1201"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}