{"id":1149,"date":"2019-05-27T23:47:00","date_gmt":"2019-05-27T23:47:00","guid":{"rendered":"https:\/\/www.ampac1.com\/blog\/profiling-of-intracellular-and-extracellular-antibiotic-resistance-genes-in-tap-water\/"},"modified":"2026-05-03T20:22:10","modified_gmt":"2026-05-04T03:22:10","slug":"profiling-of-intracellular-and-extracellular-antibiotic-resistance-genes-in-tap-water","status":"publish","type":"post","link":"https:\/\/www.ampac1.com\/blog\/profiling-of-intracellular-and-extracellular-antibiotic-resistance-genes-in-tap-water\/","title":{"rendered":"Profiling of intracellular and extracellular antibiotic resistance genes in tap water"},"content":{"rendered":"<p><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0005\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Han<\/span><span class=\"text surname\">Hao<\/span><span id=\"baff0005\" class=\"author-ref\"><sup>a<\/sup><\/span><span id=\"bfn0005\" class=\"author-ref\"><sup>1<\/sup><\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0010\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Dan-yang<\/span><span class=\"text surname\">Shi<\/span><span id=\"baff0010\" class=\"author-ref\"><sup>b<\/sup><\/span><span id=\"bfn0005\" class=\"author-ref\"><sup>1<\/sup><\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0015\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Dong<\/span><span class=\"text surname\">Yang<\/span><span id=\"baff0010\" class=\"author-ref\"><sup>b<\/sup><\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0020\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Zhong-wei<\/span><span class=\"text surname\">Yang<\/span><span id=\"baff0010\" class=\"author-ref\"><sup>b<\/sup><\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0025\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Zhi-gang<\/span><span class=\"text surname\">Qiu<\/span><span id=\"baff0010\" class=\"author-ref\"><sup>b<\/sup><\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0030\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Wei-li<\/span><span class=\"text surname\">Liu<\/span><span id=\"baff0010\" class=\"author-ref\"><sup>b<\/sup><\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0035\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Zhi-qiang<\/span><span class=\"text surname\">Shen<\/span><span id=\"baff0010\" class=\"author-ref\"><sup>b<\/sup><\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0040\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Jing<\/span><span class=\"text surname\">Yin<\/span><span id=\"baff0010\" class=\"author-ref\"><sup>b<\/sup><\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0045\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Hua-ran<\/span><span class=\"text surname\">Wang<\/span><span id=\"baff0010\" class=\"author-ref\"><sup>b<\/sup><\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0050\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Jun-wen<\/span><span class=\"text surname\">Li<\/span><span id=\"baff0010\" class=\"author-ref\"><sup>b<\/sup><\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0055\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Hui<\/span><span class=\"text surname\">Wang<\/span><span id=\"baff0005\" class=\"author-ref\"><sup>a<\/sup><\/span><\/span><\/a><a class=\"author size-m workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub#!\" name=\"baut0060\" rel=\"nofollow noopener\" target=\"_blank\"><span class=\"content\"><span class=\"text given-name\">Min<\/span><span class=\"text surname\">Jin<\/span><span id=\"baff0010\" class=\"author-ref\"><sup>b<\/sup><\/span><\/span><\/a>\\\\n<\/p>\n<h2 class=\"section-title u-h3 u-margin-l-top u-margin-xs-bottom\">Abstract<\/h2>\n<p>\\\\n<\/p>\n<div id=\"abst0010\">\\\\n<\/p>\n<p id=\"spar0035\"><a href=\"https:\/\/www.ampac1.com\/blog\/moving-from-the-traditional-paradigm-of-pathogen-inactivation-to-controlling-antibiotic-resistance-in-water-role-of-ultraviolet-irradiation\/\">Antibiotic<\/a> resistance genes, or ARGs, are a big deal globally because they threaten public health. These genes can spread antibiotic resistance even when they&#8217;re &#8220;free-living&#8221; in nature, helping resistant bacteria move into our drinking water systems. But here&#8217;s the kicker: we haven&#8217;t really looked into how much eARG pollution is in our tap water. So, we spent a year checking tap water samples from Tianjin, China, for both eARGs (extracellular ARGs) and iARGs (intracellular ARGs).<\/p>\n<p>\\\\n<\/p>\n<p>What did we find? We saw fourteen types of eARGs, with the highest concentration hitting 1.3 x 10<sup>5<\/sup> gene copies (GC)\/L. We found <em>TetC<\/em> in 66.7% of samples. Then came <em>sul1, sul2<\/em>, and <em>qnrA<\/em>, each showing up in 41.7% of samples. For iARGs, we found fifteen types, including <em>tetA, tetB, tetM, tetQ, tetX, sul1, sul2, sul3, ermB, blaTEM,<\/em> and <em>qnrA<\/em>. These were consistently in all tap water samples we collected, with <em>sul1<\/em> and <em>sul2<\/em> being the most common.<\/p>\n<p>\\\\n<\/p>\n<p>Interestingly, both eARG and iARG levels in tap water followed a seasonal pattern. They were most common in the summer. We also noticed a strong link between the amount of intracellular sulfonamide resistance genes and total nitrogen levels. This study really points out that eARG and iARG pollution in our drinking water systems could be a serious risk to everyone&#8217;s health.<\/p>\n<p>\\\\n<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304389418310239?via%3Dihub<\/a>\\\\n\\\\n<\/div>\n<p>\\\\nThe post <a href=\"https:\/\/thefactsaboutwater.org\/profiling-of-intracellular-and-extracellular-antibiotic-resistance-genes-in-tap-water\/\" rel=\"nofollow noopener\" target=\"_blank\">Profiling of intracellular and extracellular antibiotic resistance genes in tap water<\/a> appeared first on <a href=\"https:\/\/thefactsaboutwater.org\" rel=\"nofollow noopener\" target=\"_blank\">Facts About Water<\/a>.\\\\n\\\\nSource: Water Feed<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Antibiotic resistance genes (ARGs) have gained global attention due to their public health threat.<\/p>\n","protected":false},"author":1,"featured_media":87989,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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